Gut feelings about the endocannabinoid system
نویسندگان
چکیده
منابع مشابه
Gut feelings about the endocannabinoid system.
Stemming from the centuries-old and well known effects of Cannabis on intestinal motility and secretion, research on the role of the endocannabinoid system in gut function and dysfunction has received ever increasing attention since the discovery of the cannabinoid receptors and their endogenous ligands, the endocannabinoids. In this article, some of the most recent developments in this field a...
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The perspective that eating and obesity are linked to depressive disorders has gained considerable purchase, in part, because of the attention devoted to obesity in general, the finding that obesity is accompanied by a 25% increase of anxiety and depressive disorders, and because of reports linking obesity and depression to heart disease1 as well as other conditions that involve inflammatory fa...
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Obesity is characterised by altered gut microbiota, low-grade inflammation and increased endocannabinoid (eCB) system tone; however, a clear connection between gut microbiota and eCB signalling has yet to be confirmed. Here, we report that gut microbiota modulate the intestinal eCB system tone, which in turn regulates gut permeability and plasma lipopolysaccharide (LPS) levels. The impact of th...
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ژورنال
عنوان ژورنال: Neurogastroenterology & Motility
سال: 2011
ISSN: 1350-1925
DOI: 10.1111/j.1365-2982.2011.01689.x